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Cholinesterase inhibitors answers (63)

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Q: 

cholinesterase inhibitors for AD

A: And at the moment, there are no published long-term trials directly comparing all 3 cholinesterase inhibitors which are cholinergic drugs ? donepezil, galantamine, and rivastigmine. Further evidence and studies goes on to state that these same drugs are being trialled for MCI (Myocardial Infarct) patients and appears to be successful. So, it looks like yes, there is a LITTLE improvement. Quote: "...Patients suffered more adverse effects, such as nausea, vomiting, and diarrhea on the drugs, than on the placebo, but these side effects are not so bad that they outweigh the benefits," Ms. Birks said. "From the evidence provided by one trial there appear to be fewer adverse events associated with donepezil compared with...


Q: 

What Are Acetylcholinesterase inhibitors?

A: Acetylcholinesterase inhibitors, also known as anti-cholinesterase, are drugs that slow down the action of cholinesterase or acetylcholinesterase. This is an enzyme involved in the neural processes in the brain. cholinesterase turns acetylcholine into choline and acetic acid in a brain process in which cholinergic neurons go from an active to a resting state.. Low levels of acetylcholinesterase are associated with Alzheimer`s disease, and acetylcholinesterase inhibitors have been shown to stabilize dementia in Alzheimer`s patients. They work by increasing the...


Q: 

What Are the Different Types of Dementia Medication?

A: Different types of dementia affect many people as they age, but the good news is that while it is not curable, it is often treatable. Despite the fact that dementia medication cannot completely stop the condition from worsening, nor reverse damage already done, it can usually slow its progression, reduce the symptoms, and generally improve the quality of life. The majority of the drugs that have been approved for dementia focus on improving symptoms associated with Alzheimer''s disease, as this condition accounts for the majority of dementia cases. Most forms of dementia medication are considered cholinesterase inhibitors, which can help improve memory, though another drug called memantine gets the same results using a different method....


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What Are the Most Common Dementia Treatments?

A: Dementia is a condition in which a personís mental and social characteristics are altered in a noticeable manner and interfere with normal function and behavior. There is no cure for dementia, but commonly used treatments may help to slow down symptom development or reduce symptoms to a more manageable level. The most common dementia treatments include drugs called cholinesterase inhibitors and a drug called memantine, which help to minimize symptoms related to memory; increase oneís ability to learn and process new information; improve self-confidence; reduce feelings of anxiety; and help alleviate other symptoms caused by abnormal brain activity. Additionally, other medications may be used to treat the underlying conditions that...


Q: 

galantaMind history and effectiveness

A: I think you might mean galantamine. It is a cholinesterase inhibitor, it keeps more acetylcholine around for longer. Acetylcholine is linked to memory. Galantamine was the most recent med in this class to be apporved for Alzheimer''s treatment  by the Federal Government arm the FDA.  It was approved for treatment in 2001. The drug is much older than that and has been around for a longer period of time.  It works pretty much the same was as aricept and exelon.  It is typically taken twice a day but also comes in a long acting capsule.  The big issue is which cholinesterase inhibitor is best, compared to the others if any. That debate rages on, depending on who you talk to.  Aricept is older at came out in 1996....
Q: 

Huperzine A: Can it treat Alzheimer''s?

A: Huperzine (HOOP-er-zeen), a dietary supplement derived from the Chinese club moss Huperzia serrata, has received some interest as a potential treatment for Alzheimer''s disease. Huperzine A acts as a cholinesterase inhibitor — a group of medications that work by improving the levels of neurotransmitters in the brain. Small early studies suggest that huperzine A may improve memory and protect nerve cells, which could slow the cognitive decline associated with Alzheimer''s. More studies are needed, however, to determine possible benefits and long-term risks of huperzine A. For now, most doctors don''t recommend taking huperzine A because FDA-approved cholinesterase inhibitor medications are available that have been tested for safety and...


Q: 

Medications and supplements

A: Hi Marla, First off, it"s really important that the person have an accurate diagnosis, done by a geriatric psychiatrist or neurologist with a specialty in dementias. There are many, many causes of dementia. Drugs that help one kind that can actually make other kinds worse. It is also common for older people to have more than one illness causing dementia at the same time. For example, many people have Alzheimer"s and are also having mini-strokes. If only a general practitioner has put the label of Alzheimer"s on a person, you will want to ask to be referred to a specialist to confirm that is exactly what is going on, so you can be sure that the person is getting appropriate medications. Lewy Body dementia is a common cause of dementia, and people with this illness can be made very ill by...


Q: 

Is Exelon the best medication out there for Alzheimer''s disease?

A: Currently, there are no drugs to cure Alzheimer. Drugs available are used to control symptoms to improve quality of life and to slow the progression of the disease. Some categories of drugs are: Acetyl cholinesterase inhibitors, MNDA receptor antagonists and antioxidants. Available acetyl cholinesterase inhibitors on the market are Aricept (donepezil), Exelon (rivastigmine) and Razadyne (galantamine). These drugs are approved for mild-to-moderate Alzheimer''s disease. These drugs have been shown to have a modest effect on slowing cognitive losses. There have been no head-to-head comparison studies of these drugs and there is no evidence one is more efficacious than the other. Keep in mind...


Q: 

partial hip replacement with having ad

A: Hello Lisa:  I"m sorry to hear about your Mother"s increasing problems.  I"ve heard of many instances where surgery or the anesthesia, or both, may have contributed to a progression of the dementia. I would guess there is a small chance she could recover some of her cognitive and functional abilities as the anesthesia is finally out of the brain--but, when you"re dealing with such a complex organ as the brain, it"s really difficult to say with any certainty.  Certainly, keeping her well hydrated and stimulated mentally may help.  I would hope she is on anti-dementia meds, which could help improve some cognitive and functional abilities for awhile.  The "gold standard" for treatment now is a combination of one of the cholinesterase

Q: 

Is ramipril bad to take if you have myastisgravitis?

A: Hi, I need to know this so I can help you. Miastenia gravis an autoimmune neuromuscular disease leading to fluctuating muscle weakness and fatiguability.- Rampril is not bad for it , but will not help you.- Acetylcholinesterase inhibitors: neostigmine and pyridostigmine can improve muscle function by slowing the natural enzyme cholinesterase that degrades acetylcholine in the motor end plate; the neurotransmitter is therefore around longer to stimulate its receptor. Immunosuppressive drugs: prednisone, cyclosporine, mycophenolate mofetil and azathioprine may be used. It is common for patients to be treated with a combination of these drugs with a cholinesterase inhibitor. Treatments with...


 
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