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Post exposure prophylaxis answers (172)

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occupational needle sticks

A: Response from Dr. Wohl It is true that the data we have on PEP (post exposure prophylaxis) mostly deals with AZT. However, there is no reason to think that a very potent combination such as Truvada and Kaletra would not be as, if not much more, effective. Current US guidelines sanction teh regimen you are on. It could also be that the source patient has a history of AZT treatment and/or resistance. This would further motivate the use of PEP that would be active against AZT resistant virus. The risk is a function of the inoculum (size of the needle, bore, viral load of the patient), and the depth of penetration. That you started therapy quickly is a plus. In general, the risk of transmission without PEP is about 1...


Why Combivir is taken for 28 day

A: Response from Dr. Young Hello and thank you for your post. post-exposure prophylaxis is prescribed for 28 days based on the results of earlier studies that showed that shorter duration of treatment was not as effective. If you''re having difficulty with side effects or adherence, please discuss your situation with your healthcare provider. Best of luck,BY...


HIV-1 DNA by PCR test and HIV-1 Abs test

A: Response from Dr. McGowan Shortly after an exposure the HIV ab test may not have time to turn positive. Usually the earliest would be by 2 weeks and most will be positive by 6 weeks. We repeat the testing for 3 months to be sure to catch all positives. The HIV PCR test should be positive by day 36, usually at a high titer. We generally would not run this test unless a person had symtoms of seroconversion (fever, swollen glands, rash, sores in the mouth, etc). In that circumstance it should be postive and would be highly unlikely to be ''false negative'' The one caveat would be if you took post-exposure prophylaxis for 4 weeks which might delay the virus growth in the...


Could I have acquired rabies from this squirrel?

A: I''ve been told that rabies shots hurt like hell, but if you are truly as concerned as you seem from your post, I don''t see a reason (except financially speaking) not to get one. The next time you get the flu, are you literally going to believe you are dying from an incurable disease?...


syphilis tests outcome

A: Hello Sam, I"m sorry you are so worked up over this. I think the problem is more your fear of having these diseases, than the actual diseases themselves. You already had conclusive tests to substantiate that you NEVER had syphilis. The FTA ABS and TPPA are very definitive tests that "once positive, will always remain positive" meaning that evidence for past infection will almost always remain, even though you were effectively treated. The topical medications you had prescribed for your face will not affect your having a false positive or a false negative blood test for syphilis or HIV, for that matter. You should have a conversation with a trusted health care provider, who can reassure you that you are okay medically. There are no good reasons to search for a disease or infection that...



A: There is something called post exposure prophylaxis that can reduce the likelihood of transmission but it is not generally open to the public. It"s usually given to rape victims, healthcare workers who are stuck with syringes etc. The general public is expected to use condoms and other means to prevent HIV transmission....


I waxed someones eyebrow and wiped a drop of blood with my glove. A few minutes later, I put a stick

A: Hello,Although HIV and hepB virus don?t survive outside the body,but cases have been reported in which accidentalingestion of blood of an infected individual has lead to transmission of these two virus esp if there is asore or cut in the mouth.I would suggest getting yourself tested(by ELISA) for HIV and post exposureprophylaxis.Pls consult a physician or infectious diseases specialist soon.Best.....

Rabies - Advice Needed

A: Hello Goldberg, Let me go through a few facts about rabies: Rabies is uncommon in dogs, cats, and ferrets in the United States. Very few bites by these animals carry a risk of rabies. If the cat (or dog or ferret) appeared healthy at the time you were bitten, it can be confined by its owner for 10 days and observed. No anti-rabies prophylaxis is needed. No person in the United States has ever contracted rabies from a dog, cat or ferret held in quarantine for 10 days. If a dog, cat, or ferret appeared ill at the time it bit you or becomes ill during the 10 day quarantine, it should be evaluated by a veterinarian for signs of rabies and you should seek medical advice about the need for anti-rabies prophylaxis. The quarantine period is a...


Incubation period

A: Welcome to AllExperts dear Cris. It depends on the situation and the context. Following are two possible situations and possible time-frames: Partner - Unknown HIV Status The time it takes for people to have produced enough antibodies varies; anywhere from 2 to 8 weeks or longer, with the average being about 25 days. But this can vary from person to person so a good rule of thumb to follow is if your negative test was done less than 3 months after your potential exposure, you should get another test after 3 months time. While about 97% of people will develop HIV antibodies after an infection, it may take 6 months to produce antibodies in some cases. Partner - Known HIV Positive exposure to a known HIV positive partner is a...


Recieved oral sex with cut on penis. Please help.

A: Hello Tyrone, It is highly UNLIKELY, that even if your sex partner was HIV infected, with bleeding gums, that you would get infected from this contact. There is a theoretical risk, however, and there is no good way to know unless both of you submitted to the immediate HIV antibody test (finger stick or oral) at the same time. Your negative test would reassure her that you were not infected (at least 3 months prior to the incident); and your partner"s negative test would reassure you that he or she was not infected (at least 3 months prior to the incident). post exposure prophylaxis is an expensive option in some countries, but you"d need to contact your city or state health department, or the national HIV phone...

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