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What is dcis? answers (2890)

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Q: 

52 y/o premenopausal (we think; taking LoEstrin for 7 yrs -- perimenopause). Lumpectomy and SLN biopsy Jan,?05. Discovered from microcalcifications on annual screening mammo. Rad onc says invasive ductal adenocarcinoma. Path report says invasive tumor: tubulolobular carcinoma. Mod B&R grade 1. Dimension 1.1cm. Clear margins. Necrosis, lymphovascular, and perineural invasion all absent. ER+ (>90% of tumor cells); PR+ (15-20%).HER-2/neu unamplified, ratio= 0.85. DCis: grade=low, cribriform, papillary. DCis dimension 1cm. Extent w/in invasive tumor 30-40%. Does extend beyond invasive. Clear margins; microcalcifications present w/in DCis. SLN biopsy negative. Questions: 1)where can I find info on tubulolobular? Little info I find seems to indicate disagreement on whether it is actually ductal or lobular, but sounds like it has good prognosis. 2)My oncologist told me the 30-40% DCis w/in invasive indicates invasive actually only about 6 or 7 mm; correct? 3)what about DCis with invasive? I have read somewhere that low grade DCis w/in invasive was good prognostic indicator; correct? I am having radiation and will follow with tamoxifen. Sound good? Thanks for your wonderful site!

A: her pathology is unusual enough (and yes there is a question of whether this is ductal or lobular) that you might want to consider sending the pathology slides to another institution for a second reading to unravel the mystery. a place like ours or Vanderbilt where there are pathologists who specialize in breast cancer. one of the questions is whether the invasive component ''skips''--- invasive, then dcis, then invasive or not. hopefully off HRT now. hormonal therapy will be part of the game plan more than likely. you might find information you are seeking at www.cancerfacts.com...
Q: 

In one of your replys, concerning calcifications or an increase in calcifciations near a previously biopsied site, you stated that a stereotactic biopsy is commonly done again to ruleout the presecence of dcis. Could you explain a sterotactic biopsy and what is dcis?

A: stereotactic biopsy uses a large guage needle guided by a computer and mammogram to sample tiny calcifications. no incision. no scar. done in breast imaging. dcis is noninvasive breast cancer. stage 0 disease. ductal carcinoma insitu....


Q: 

what is dcis?

A: Ductal Carcinoma, maybe some type of breast cancer. Also is Defense Criminal Investigative Service. It''s like NCis except for the Army....


Q: 

Hello from Canada: I recently had a wide excision lumpectomy , left breast, with sentinel lymph node procedure at same time. My path report was Pagets nipple with DCis of high grade, but in only one block of tissue specimen. Sentinel node revealed only reactive hyperplasia, no metastatic carcinoma. Told this is Stage 0. I am presently undergoing radiation,25 treatments, in all and have just 9 to go.. what should I know in order to decide whether to go on Tamoxifan or a like drug? I want to do all I can to become and stay cancer free, but I do not understand why DCis, even high grade, has to be treated with more than surgery and radiation. I do not know if my cancer was hormone dependent and have been told that DCis is not tested for hormone dependency, so how does one know what % the Tamoxifan would improve ones situation? As well, what % of DCis reoccurs, either as DCis or an invasive cancer? I was under the understanding that DCis may be there for years and even without and treatment may not ever change into an invasive cancer, what do the stats say on all of this?I should add I am in perfect health except for the DCis, and am 61 years young. Any further advice or information would be greatly appreciated. Thanks so much and I hope the answers to my questions may be of help to others in same type of situation

A: The good news is that it is stage 0 breast cancer. we don''t know what % of patients with DCis progress to invasive disease. But this isn''t the time to play russian roulet and hope that you aren''t among those whose disease progresses. so lumpectomy and radiation are commonly what are recommended. Additionall DCis CAN and should be tested for hormone receptivity. so if the pathology dept isn''t accustomed to doing it then take your slides to another pathology location where they do. that is...


Q: 

52 y/o premenopausal (we think; taking LoEstrin for 7 yrs -- perimenopause). Lumpectomy and SLN biopsy Jan,?05. Discovered from microcalcifications on annual screening mammo. Rad onc says invasive ductal adenocarcinoma. Path report says invasive tumor: tubulolobular carcinoma. Mod B&R grade 1. Dimension 1.1cm. Clear margins. Necrosis, lymphovascular, and perineural invasion all absent. ER+ (>90% of tumor cells); PR+ (15-20%).HER-2/neu unamplified, ratio= 0.85. DCis: grade=low, cribriform, papillary. DCis dimension 1cm. Extent w/in invasive tumor 30-40%. Does extend beyond invasive. Clear margins; microcalcifications present w/in DCis. SLN biopsy negative. Questions: 1)where can I find info on tubulolobular? Little info I find seems to indicate disagreement on whether it is actually ductal or lobular, but sounds like it has good prognosis. 2)My oncologist told me the 30-40% DCis w/in invasive indicates invasive actually only about 6 or 7 mm; correct? 3)what about DCis with invasive? I have read somewhere that low grade DCis w/in invasive was good prognostic indicator; correct? I am having radiation and will follow with tamoxifen. Sound good? Thanks for your wonderful site!

A: her pathology is unusual enough (and yes there is a question of whether this is ductal or lobular) that you might want to consider sending the pathology slides to another institution for a second reading to unravel the mystery. a place like ours or Vanderbilt where there are pathologists who specialize in breast cancer. one of the questions is whether the invasive component ''skips''--- invasive, then dcis, then invasive or not. hopefully off HRT now. hormonal therapy will be part of the game plan more than likely. you might find information you are seeking at www.cancerfacts.com...


Q: 

In one of your replys, concerning calcifications or an increase in calcifciations near a previously biopsied site, you stated that a stereotactic biopsy is commonly done again to ruleout the presecence of dcis. Could you explain a sterotactic biopsy and what is dcis?

A: stereotactic biopsy uses a large guage needle guided by a computer and mammogram to sample tiny calcifications. no incision. no scar. done in breast imaging. dcis is noninvasive breast cancer. stage 0 disease. ductal carcinoma insitu....


Q: 

Does tamoxifen have any effect on DCis? what about DCis with 1.5mm of microinvasion - would tamoxifen be a benefit in this case?

A: tamoxifen doesn''t kill cancer cells, dcis or otherwise. it is designed to help prevent breast cancer cells from growing. this is applicable for cells that are stimulated to grow by estrogen....


Q: 

what is dcis? thank you!

A: ductal carcinoma insitu-- noninvasive breast cancer. stage 0 breast cancer....


Q: 

I have DCis intermediate stage. I chose to have breast conserving surgery but when I showed the surgeon my x-rays he said I was not a candidate. My DCis is over too wide an area, and he also told me it might be a combination of DCis and invasive. I am not able to find any info on-line that helps me understand why he would say something like that. I have now decided to have both breast removed (only one is positive for DCis) and immediate reconstruction. My doctor first detected a thickening in my right breast in Jan. It is now May and the waiting is killing me. I understand that mammograms miss a lot. I had a core biopsy done. Does a core biopsy tell the pathologist whether the cancer is invasive or not? Or, is it because the DCis is extensive that I have a greater risk of it being invasive. Any info would be greatly appreciated. It seems we find so many questions after the visit to the doctor that we wish we had asked at the time.

A: what is being described sounds like multicentric disease or extensive DCis which is occupying more than one quadrant of the breast making lumpectomy not the recommended choice since so much breast tissue would need to be removed. Extensive DCis can have small amounts if invasive disease buried in it somewhere so physicians sometimes mention this issue. sentinel node biopsy with mastectomy in such a case is commonly done too just in case any invasion is found by pathology. Pathology can tell in...
 
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